"Patients with Parkinson's disease (PD) present with a variety of non-motor symptoms including sensory complaints and mood disturbances. In the current pilot study, we aimed to explore pain complaints and the association between mood and pain in PD," scientists writing in the International Journal of Geriatric Psychiatry report.
"We hypothesized that pain ratings would be elevated in patients with PD relative to controls. As PD is lateralized at onset and studies have found lateralization of some non-motor symptoms in PD, we also hypothesized that PD patients would exhibit differing pain profiles depending on side of onset of the disease. Twenty-three PD patients (11 right-onset (RPD), 12 left-onset (LPD) disease), and 11 control participants (CS) completed a mood questionnaire (Depression Anxiety Stress Scale; DASS) as well as the short form of the McGill Pain Questionnaire. Both PD groups reported higher present pain intensity scores (p = 0.001), more evaluative pain intensity (p = 0.02), and more overall pain (p = 0.02) than control participants. There was a significant association between mood and all of the McGill pain ratings in the LPD patients, with those reporting more mood symptoms rating higher on all pain scales (all p-values < 0.001). This association was not found in the RPD group. Our results suggest an association between mood and pain in patients with PD that may be related to the differential contribution of right-hemispheric neural networks in processing of mood and pain states," wrote P. Mcnamara and colleagues, Boston University, Medical Department.
The researchers concluded: "These findings merit further investigation into the relation between mood and pain in patients with PD."
Mcnamara and colleagues published their study in International Journal of Geriatric Psychiatry (Mood, side of motor symptom onset and pain complaints in Parkinson's disease. International Journal of Geriatric Psychiatry, 2010;25(5):519-524).
Additional information can be obtained by contacting P. Mcnamara, Boston University, School Medical, Dept. of Neurology, Boston, MA 02118, USA.
The publisher of the International Journal of Geriatric Psychiatry can be contacted at: John Wiley & Sons Ltd., the Atrium, Southern Gate, Chichester PO19 8SQ, W Sussex, England.
Keywords: City:Boston, State:MA, Country:United States, Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, Movement Disorders, Neurodegenerative Diseases, Parkinson Disease, Parkinsonian Disorders, Psychiatry
This article was prepared by Psychology & Psychiatry Journal editors from staff and other reports. Copyright 2010, Psychology & Psychiatry Journal via NewsRx.com.
Source Citation
"Research conducted at Boston University, Medical Department has provided new information about Parkinson disease." Psychology & Psychiatry Journal 12 June 2010: 184. Health Reference Center Academic. Web. 7 June 2010.
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Disclaimer:This information is not a tool for self-diagnosis or a substitute for professional care
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