Thursday, May 27, 2010

27. Lovely literature

27. Lovely literature, originally uploaded by C-Trick.
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New research, 'Transpedicular closed wedge osteotomy in ankylosing spondylitis: results of surgical treatment and prospective outcome analysis,' is the subject of a report. "Surgery in late stage ankylosing spondylitis (AS) most often tends to correct the sagittal balance with an extension osteotomy of the spine. In the literature, extension osteotomy was first described as an open wedge osteotomy but recently closed wedge osteotomy resecting the pedicles and posterior elements have become more popular," scientists in Copenhagen, Denmark report (see also Ankylosing Spondylitis).

"Only a limited number of cases have been reported in the literature and with limited focus on outcome of this major surgery. In this study, we reported the results of a large series of extension osteotomy in a population of patients with AS focusing on the technical aspects, complication rates, correction obtained and outcome evaluation using newer spine outcome measuring instruments. In the period from 1995 to 2005, 36 consecutive patients fulfilled the criteria where the files, radiographs and patients were available for further studies. The following data were recorded: Age, sex, comorbidity, indication, operation time and blood loss, level of osteotomy and estimated Correction. Furthermore, perioperative complications and all late complications were registered. The average follow-up was 50 months (3-128). Twenty-one patients also filled out questionnaires (SF36 and Oswestry Disability Index) preoperatively. At the end of the period all patients were contacted and filled out the same questionnaires. Fifteen of the patients had two pedicular resection osteotomies performed, 21 had one, and two had polysegmental osteotomies. Mean operation time was 180 min, bleeding was mean 2,450 ml, stay at the hospital was 13 days. One patient had partial paresis of the lower extremities all other complications were minor. The median correction was 45 degrees. The median Oswestry score improved significantly from 54 (range 20-94) preoperatively to 38 (range 2-94) postoperatively. The SF-36 score significantly increased, when evaluated on the major components Physical Component Summary (PCS) and Mental Component Summary (MCS). The thoracolumbar closed wedge pedicular resection osteotomy used in this series was a safe method for correction of incapacitating kyphosis in AS. There was an acceptable rate of perioperative complications and no mortality. The correction obtained was in average 45 degrees. All of the patients except one maintained their good correction and restored function. Outcome analysis showed a significant improvement in SF-36 and Oswestry Disability Index, and the mental component of the SF-36 showed improvement to values near the normative population," wrote T. Kiaer and colleagues, National University, Department of Orthopaedic Surgery.

The researchers concluded: "It is concluded that corrective osteotomy of the thoracolumbar spine in AS is an effective and safe treatment with improvements in quality of life."

Kiaer and colleagues published their study in European Spine Journal (Transpedicular closed wedge osteotomy in ankylosing spondylitis: results of surgical treatment and prospective outcome analysis. European Spine Journal, 2010;19(1):57-64).

For additional information, contact T. Kiaer, National University Hospital, Dept. of Orthopaedic Surgery, Spine Section, Rigshospitalet, Copenhagen, Denmark.

The publisher's contact information for the European Spine Journal is: Springer, 233 Spring Street, New York, NY 10013, USA.

Keywords: City:Copenhagen, Country:Denmark, Ankylosing Spondylitis, Infection, Infectious Bone Diseases, Osteotomy, Rheumatology, Spinal Diseases, Surgery.

This article was prepared by Medical Devices & Surgical Technology Week editors from staff and other reports. Copyright 2010, Medical Devices & Surgical Technology Week via

Source Citation
"New ankylosing spondylitis research from National University, Department of Orthopaedic Surgery outlined." Medical Devices & Surgical Technology Week 30 May 2010: 59. General OneFile. Web. 27 May 2010.
Document URL

Gale Document Number:A226880397

Disclaimer:This information is not a tool for self-diagnosis or a substitute for professional care.

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